Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study
Introduction. Obesity is an established risk factor for cancer and cancer-related deaths, including that of the breast. While the prevalence of female obesity has accelerated over the past decade in many developing countries, such as Colombia, the prevalence of overweight and obesity specifically in...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.1155/2017/9574874 |
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| author | Javier Cuello-López Ana Fidalgo-Zapata Elsa Vásquez-Trespalacios |
| author_facet | Javier Cuello-López Ana Fidalgo-Zapata Elsa Vásquez-Trespalacios |
| author_sort | Javier Cuello-López |
| collection | DOAJ |
| description | Introduction. Obesity is an established risk factor for cancer and cancer-related deaths, including that of the breast. While the prevalence of female obesity has accelerated over the past decade in many developing countries, such as Colombia, the prevalence of overweight and obesity specifically in breast cancer populations has not been fully described. Methods. A cross-sectional study including 849 women diagnosed with breast cancer between 2009 and 2014. Based on body mass index, prevalence of overweight (BMI ≥ 25 < 30) and obesity (BMI ≥ 30) and associations of BMI with clinical and tumor histopathological features were analyzed. Results. Colombian breast cancer patients had a prevalence of overweight of 34.28% and obesity of 28.15%. Mean BMI was comparable between premenopausal and postmenopausal women (27.2 versus 27.7, resp.). Among premenopausal women, higher BMI was significantly positively associated with hormone receptor negative tumors, as well as with greater lymphovascular invasion. Conclusions. Colombian breast cancer patients exhibit a significant prevalence of overweight and obesity. Associations of high BMI and poor prognosis variables in the premenopausal population suggest risk of aggressive disease in this population. Future studies to further validate our observations are warranted in order to implement multidisciplinary clinical guidelines. |
| format | Article |
| id | doaj-art-852d89a6baba49de9368c3bfe6227cc2 |
| institution | Kabale University |
| issn | 2090-3170 2090-3189 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-852d89a6baba49de9368c3bfe6227cc22025-02-03T05:45:14ZengWileyInternational Journal of Breast Cancer2090-31702090-31892017-01-01201710.1155/2017/95748749574874Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional StudyJavier Cuello-López0Ana Fidalgo-Zapata1Elsa Vásquez-Trespalacios2Clinical Oncology Group, Fundación Colombiana de Cancerología-Clínica Vida, Medellín, ColombiaBreast Surgeon Fellowship Program, School of Medicine, CES University, Medellín, ColombiaDepartment of Clinical Epidemiology, School of Medicine, CES University, Medellín, ColombiaIntroduction. Obesity is an established risk factor for cancer and cancer-related deaths, including that of the breast. While the prevalence of female obesity has accelerated over the past decade in many developing countries, such as Colombia, the prevalence of overweight and obesity specifically in breast cancer populations has not been fully described. Methods. A cross-sectional study including 849 women diagnosed with breast cancer between 2009 and 2014. Based on body mass index, prevalence of overweight (BMI ≥ 25 < 30) and obesity (BMI ≥ 30) and associations of BMI with clinical and tumor histopathological features were analyzed. Results. Colombian breast cancer patients had a prevalence of overweight of 34.28% and obesity of 28.15%. Mean BMI was comparable between premenopausal and postmenopausal women (27.2 versus 27.7, resp.). Among premenopausal women, higher BMI was significantly positively associated with hormone receptor negative tumors, as well as with greater lymphovascular invasion. Conclusions. Colombian breast cancer patients exhibit a significant prevalence of overweight and obesity. Associations of high BMI and poor prognosis variables in the premenopausal population suggest risk of aggressive disease in this population. Future studies to further validate our observations are warranted in order to implement multidisciplinary clinical guidelines.http://dx.doi.org/10.1155/2017/9574874 |
| spellingShingle | Javier Cuello-López Ana Fidalgo-Zapata Elsa Vásquez-Trespalacios Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study International Journal of Breast Cancer |
| title | Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study |
| title_full | Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study |
| title_fullStr | Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study |
| title_full_unstemmed | Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study |
| title_short | Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study |
| title_sort | obesity and prognostic variables in colombian breast cancer patients a cross sectional study |
| url | http://dx.doi.org/10.1155/2017/9574874 |
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