Comprehensive structural and functional analyses of RAD50 nsSNPs: from prediction to impact assessment
BackgroundThe RAD50 gene on chromosome 5q3.11 plays an important role in the MRN (Mre11–Rad50–Nbs1) complex. This complex orchestrates cellular responses to the DNA double-strand breaks (DSBs) through several pathways for genome stability. This study aims to investigate the functional impact of non-...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-03-01
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| Series: | Frontiers in Bioinformatics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2025.1535482/full |
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