Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound

Introduction. A number of studies suggest that oxygen-ozone therapy may have a role in the treatment of chronic, nonhealing, or ischemic wounds for its disinfectant and antibacterial properties. Nonhealing wounds are a significant cause of morbidity. Here we present a case of subcutaneous oxygen-ozo...

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Main Authors: Irene Degli Agosti, Elena Ginelli, Bruno Mazzacane, Gabriella Peroni, Sandra Bianco, Fabio Guerriero, Giovanni Ricevuti, Simone Perna, Mariangela Rondanelli
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2016/9528572
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author Irene Degli Agosti
Elena Ginelli
Bruno Mazzacane
Gabriella Peroni
Sandra Bianco
Fabio Guerriero
Giovanni Ricevuti
Simone Perna
Mariangela Rondanelli
author_facet Irene Degli Agosti
Elena Ginelli
Bruno Mazzacane
Gabriella Peroni
Sandra Bianco
Fabio Guerriero
Giovanni Ricevuti
Simone Perna
Mariangela Rondanelli
author_sort Irene Degli Agosti
collection DOAJ
description Introduction. A number of studies suggest that oxygen-ozone therapy may have a role in the treatment of chronic, nonhealing, or ischemic wounds for its disinfectant and antibacterial properties. Nonhealing wounds are a significant cause of morbidity. Here we present a case of subcutaneous oxygen-ozone therapy used to treat a nonhealing postoperative wound in a young man during a period of 5 weeks. Case Presentation. A 46-year-old man had a motorcycle accident and underwent amputation of the right tibia and fibula. At the discharge he came to our attention to start rehabilitation treatment. At that time the wound was ulcerated but it was afebrile with no signs of inflammation and negativity to blood tests. At 2 months from the trauma despite appropriate treatment and dressing, the wound was slowly improving and the patient complained of pain. For this reason in addition to standard dressing he underwent oxygen-ozone therapy. After 5 weeks of treatment the wound had healed. Conclusion. In patients with nonhealing wounds, oxygen-ozone therapy could be helpful in speeding the healing and reducing the pain thanks to its disinfectant property and by the increase of endogenous oxygen free radicals’ scavenging properties. Compared to standard dressing and other treatments reported in the literature it showed a shorter time of action.
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spelling doaj-art-851710c49a194f93a0a4f1972a72ec7b2025-02-03T01:00:10ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/95285729528572Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic WoundIrene Degli Agosti0Elena Ginelli1Bruno Mazzacane2Gabriella Peroni3Sandra Bianco4Fabio Guerriero5Giovanni Ricevuti6Simone Perna7Mariangela Rondanelli8Rehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, ItalyRehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, ItalyRehabilitation Unit, Azienda di Servizi alla Persona di Pavia, 27100 Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, ItalySection of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, ItalySection of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, ItalySection of Geriatrics, Department of Internal Medicine and Medical Therapy, University of Pavia, 27100 Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, ItalyDepartment of Public Health, Experimental and Forensic Medicine, School of Medicine, Endocrinology and Nutrition Unit, University of Pavia, Pavia, ItalyIntroduction. A number of studies suggest that oxygen-ozone therapy may have a role in the treatment of chronic, nonhealing, or ischemic wounds for its disinfectant and antibacterial properties. Nonhealing wounds are a significant cause of morbidity. Here we present a case of subcutaneous oxygen-ozone therapy used to treat a nonhealing postoperative wound in a young man during a period of 5 weeks. Case Presentation. A 46-year-old man had a motorcycle accident and underwent amputation of the right tibia and fibula. At the discharge he came to our attention to start rehabilitation treatment. At that time the wound was ulcerated but it was afebrile with no signs of inflammation and negativity to blood tests. At 2 months from the trauma despite appropriate treatment and dressing, the wound was slowly improving and the patient complained of pain. For this reason in addition to standard dressing he underwent oxygen-ozone therapy. After 5 weeks of treatment the wound had healed. Conclusion. In patients with nonhealing wounds, oxygen-ozone therapy could be helpful in speeding the healing and reducing the pain thanks to its disinfectant property and by the increase of endogenous oxygen free radicals’ scavenging properties. Compared to standard dressing and other treatments reported in the literature it showed a shorter time of action.http://dx.doi.org/10.1155/2016/9528572
spellingShingle Irene Degli Agosti
Elena Ginelli
Bruno Mazzacane
Gabriella Peroni
Sandra Bianco
Fabio Guerriero
Giovanni Ricevuti
Simone Perna
Mariangela Rondanelli
Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
Case Reports in Medicine
title Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
title_full Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
title_fullStr Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
title_full_unstemmed Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
title_short Effectiveness of a Short-Term Treatment of Oxygen-Ozone Therapy into Healing in a Posttraumatic Wound
title_sort effectiveness of a short term treatment of oxygen ozone therapy into healing in a posttraumatic wound
url http://dx.doi.org/10.1155/2016/9528572
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