Exploring a patient-specific in vitro pipeline for stratification and drug response prediction of microglia-based therapeutics

Abstract The scarcity of effective biomarkers and therapeutic strategies for predicting disease onset and progression in neurodegenerative diseases such as Alzheimer’s disease (AD) is a major challenge. Conventional drug discovery approaches have been unsuccessful in providing efficient intervention...

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Bibliographic Details
Main Authors: Carla Cuní-López, Romal Stewart, Satomi Okano, Garry L. Redlich, Mark W. Appleby, Anthony R. White, Hazel Quek
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-92593-6
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