Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends

Activity of the mammalian DNA transposon piggyBat from Myotis lucifugus is restricted by its own transposon ends

Abstract Members of the piggyBac superfamily of DNA transposons are widely distributed in host genomes ranging from insects to mammals. The human genome has retained five piggyBac-derived genes as domesticated elements although they are no longer mobile. Here, we have investigated the transposition...

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Main Authors: Alison B. Hickman, Laurie Lannes, Christopher M. Furman, Christina Hong, Lidiya Franklin, Rodolfo Ghirlando, Arpita Ghosh, Wentian Luo, Parthena Konstantinidou, Hernán A. Lorenzi, Anne Grove, Astrid D. Haase, Matthew H. Wilson, Fred Dyda
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55784-9
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