Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives
Abstract The field of extracellular vesicle (EV) research has rapidly evolved, revealing their significant roles in various biological processes and clinical applications. Allergic diseases are prevalent immunological disorders characterized by exaggerated hypersensitivity reactions to allergens, le...
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| Format: | Article |
| Language: | English |
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Wiley-VCH
2025-01-01
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| Series: | Interdisciplinary Medicine |
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| Online Access: | https://doi.org/10.1002/INMD.20240049 |
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| author | Jia Wu Yan Wang Yuqing Wang Jiawei Ribaudo Shu Li Shunyan Hu Maolin Tang Yongliang Chen Yan Long |
| author_facet | Jia Wu Yan Wang Yuqing Wang Jiawei Ribaudo Shu Li Shunyan Hu Maolin Tang Yongliang Chen Yan Long |
| author_sort | Jia Wu |
| collection | DOAJ |
| description | Abstract The field of extracellular vesicle (EV) research has rapidly evolved, revealing their significant roles in various biological processes and clinical applications. Allergic diseases are prevalent immunological disorders characterized by exaggerated hypersensitivity reactions to allergens, leading to diverse clinical manifestations that can severely impact quality of life. Recently, studies have underscored the pivotal role of EVs in allergic conditions, including asthma, allergic rhinitis, and atopic dermatitis. In this review, we provide a comprehensive overview of recent advances in the separation and characterization of EVs, their roles in allergic diseases, and their diagnostic value as biomarkers. Additionally, we explore the therapeutic potential of EVs for the treatment and prevention of allergic conditions. Overall, the emerging insights into EVs present promising opportunities for enhancing the diagnosis, treatment, and management of allergic diseases. |
| format | Article |
| id | doaj-art-84ef4b58de284764a1490f1ba820c6db |
| institution | Kabale University |
| issn | 2832-6245 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley-VCH |
| record_format | Article |
| series | Interdisciplinary Medicine |
| spelling | doaj-art-84ef4b58de284764a1490f1ba820c6db2025-01-25T17:57:32ZengWiley-VCHInterdisciplinary Medicine2832-62452025-01-0131n/an/a10.1002/INMD.20240049Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectivesJia Wu0Yan Wang1Yuqing Wang2Jiawei Ribaudo3Shu Li4Shunyan Hu5Maolin Tang6Yongliang Chen7Yan Long8Department of Clinical Laboratory Guangzhou Women and Children's Medical Center Guangdong Provincial Clinical Research Center for Child Health Guangzhou Medical University Guangzhou ChinaFirst Clinical Medical College Shanxi Medical University Taiyuan ChinaCenter of Basic Medical Research Institute of Medical Innovation and Research Peking University Third Hospital Beijing ChinaDepartment of Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry Ann Arbor Michigan USADepartment of Clinical Laboratory Guangzhou Women and Children's Medical Center Guangdong Provincial Clinical Research Center for Child Health Guangzhou Medical University Guangzhou ChinaDepartment of Clinical Laboratory Guangzhou Women and Children's Medical Center Guangdong Provincial Clinical Research Center for Child Health Guangzhou Medical University Guangzhou ChinaDepartment of Laboratory Medicine General Hospital of Southern Theater Command Guangzhou ChinaKingMed School of Laboratory Medicine Guangzhou Medical University Guangzhou ChinaDepartment of Clinical Laboratory Guangzhou Women and Children's Medical Center Guangdong Provincial Clinical Research Center for Child Health Guangzhou Medical University Guangzhou ChinaAbstract The field of extracellular vesicle (EV) research has rapidly evolved, revealing their significant roles in various biological processes and clinical applications. Allergic diseases are prevalent immunological disorders characterized by exaggerated hypersensitivity reactions to allergens, leading to diverse clinical manifestations that can severely impact quality of life. Recently, studies have underscored the pivotal role of EVs in allergic conditions, including asthma, allergic rhinitis, and atopic dermatitis. In this review, we provide a comprehensive overview of recent advances in the separation and characterization of EVs, their roles in allergic diseases, and their diagnostic value as biomarkers. Additionally, we explore the therapeutic potential of EVs for the treatment and prevention of allergic conditions. Overall, the emerging insights into EVs present promising opportunities for enhancing the diagnosis, treatment, and management of allergic diseases.https://doi.org/10.1002/INMD.20240049allergic diseasesdiagnostic markersextracellular vesiclestherapeutic agents |
| spellingShingle | Jia Wu Yan Wang Yuqing Wang Jiawei Ribaudo Shu Li Shunyan Hu Maolin Tang Yongliang Chen Yan Long Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives Interdisciplinary Medicine allergic diseases diagnostic markers extracellular vesicles therapeutic agents |
| title | Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives |
| title_full | Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives |
| title_fullStr | Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives |
| title_full_unstemmed | Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives |
| title_short | Interplay between extracellular vesicles and allergic diseases: Current insights and future perspectives |
| title_sort | interplay between extracellular vesicles and allergic diseases current insights and future perspectives |
| topic | allergic diseases diagnostic markers extracellular vesicles therapeutic agents |
| url | https://doi.org/10.1002/INMD.20240049 |
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