Nature's defense against emerging neurodegenerative threats: Dynamic simulation, PCA, DCCM identified potential plant-based antiviral lead targeting borna disease virus nucleoprotein.

Nature's defense against emerging neurodegenerative threats: Dynamic simulation, PCA, DCCM identified potential plant-based antiviral lead targeting borna disease virus nucleoprotein.

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The rare zoonotic Borna disease virus (BDV) causes fatal neurological disease in various animals, with a high mortality rate exceeding 90% in central Europe. However, unlike most viruses, it establishes persistent infections within the host cell nucleus, hindering treatment. As successful BDV treatm...

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Main Authors: Noimul Hasan Siddiquee, Md Ifteker Hossain, Farhana Mansoor Priya, Sakia Binte Azam, Md Enamul Kabir Talukder, Durjoy Barua, Salina Malek, Niloy Saha, Sidratul Muntaha, Ridoy Paul, Israt Jahan Ritu, Farjana Islam Tuly, Abir Hossain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0310802
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https://doi.org/10.1371/journal.pone.0310802

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