A self-assembled protein β-helix as a self-contained biofunctional motif

A self-assembled protein β-helix as a self-contained biofunctional motif

Abstract Nature constructs matter by employing protein folding motifs, many of which have been synthetically reconstituted to exploit function. A less understood motif whose structure-function relationships remain unexploited is formed by parallel β-strands arranged in a helical repetitive pattern,...

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Main Authors: Camilla Dondi, Javier Garcia-Ruiz, Erol Hasan, Stephanie Rey, James E. Noble, Alex Hoose, Andrea Briones, Ibolya E. Kepiro, Nilofar Faruqui, Purnank Aggarwal, Poonam Ghai, Michael Shaw, Antony T. Fry, Antony Maxwell, Bart W. Hoogenboom, Christian D. Lorenz, Maxim G. Ryadnov
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59873-1
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https://doi.org/10.1038/s41467-025-59873-1

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