Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells

Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells

Intravenously transplanted mesenchymal stromal cells (MSCs) have been shown to interact with endothelial cells and to migrate to tissues. However, intracellular signals regulating MSC migration are still incompletely understood. Here, we analyzed the role of Rap1 GTPase in the migration of human bon...

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Bibliographic Details
Main Authors: Melanie Giesen, Erika Fleck, Jürgen Scheele, Tanja Nicole Hartmann, Reinhard Henschler
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biology
Subjects:
mesenchymal stromal cells
Rap1
adhesion
integrins
chemokine receptors
Online Access:https://www.mdpi.com/2079-7737/14/1/96
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