Bilateral Renal Cortical Necrosis in Meningococcal Meningitis
Bacterial meningitis is a relatively common infection of the cerebrospinal fluid (CSF) and leptomeninges. The clinical picture evolves rapidly and, if treatment is delayed, can result in a variety of long-...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
|
| Series: | Case Reports in Nephrology |
| Online Access: | http://dx.doi.org/10.1155/2011/274341 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559013328322560 |
|---|---|
| author | C. Kennedy S. Khilji A. Dorman J. Walshe |
| author_facet | C. Kennedy S. Khilji A. Dorman J. Walshe |
| author_sort | C. Kennedy |
| collection | DOAJ |
| description | Bacterial meningitis
is a relatively common infection of the
cerebrospinal fluid (CSF) and leptomeninges. The
clinical picture evolves rapidly and, if
treatment is delayed, can result in a variety of
long-term sequelae, including death. Acute
kidney injury in the setting of bacterial
meningitis usually results from hypotension and
volume depletion and resolves with appropriate
treatment. Meningococcaemia with profound
hypotension, and/or disseminated intravascular
coagulopathy (DIC) may very rarely lead to
bilateral renal cortical necrosis. In this
context, renal recovery is extremely unlikely.
We present two cases of meningococcaemia
complicated by bilateral renal cortical necrosis
and, ultimately, end stage kidney disease. We
also present a review of the literature on the
subject. The cases outline the importance of
early aggressive intervention by a
multidisciplinary team. |
| format | Article |
| id | doaj-art-848dc56a7b0a4b80920cfa242f63f848 |
| institution | Kabale University |
| issn | 2090-6641 2090-665X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Nephrology |
| spelling | doaj-art-848dc56a7b0a4b80920cfa242f63f8482025-02-03T01:30:59ZengWileyCase Reports in Nephrology2090-66412090-665X2011-01-01201110.1155/2011/274341274341Bilateral Renal Cortical Necrosis in Meningococcal MeningitisC. Kennedy0S. Khilji1A. Dorman2J. Walshe3Department of Nephrology, Beaumont Hospital, Dublin 9, IrelandDepartment of Nephrology, Beaumont Hospital, Dublin 9, IrelandDepartment of Pathology, Beaumont Hospital, Dublin 9, IrelandDepartment of Nephrology, Beaumont Hospital, Dublin 9, IrelandBacterial meningitis is a relatively common infection of the cerebrospinal fluid (CSF) and leptomeninges. The clinical picture evolves rapidly and, if treatment is delayed, can result in a variety of long-term sequelae, including death. Acute kidney injury in the setting of bacterial meningitis usually results from hypotension and volume depletion and resolves with appropriate treatment. Meningococcaemia with profound hypotension, and/or disseminated intravascular coagulopathy (DIC) may very rarely lead to bilateral renal cortical necrosis. In this context, renal recovery is extremely unlikely. We present two cases of meningococcaemia complicated by bilateral renal cortical necrosis and, ultimately, end stage kidney disease. We also present a review of the literature on the subject. The cases outline the importance of early aggressive intervention by a multidisciplinary team.http://dx.doi.org/10.1155/2011/274341 |
| spellingShingle | C. Kennedy S. Khilji A. Dorman J. Walshe Bilateral Renal Cortical Necrosis in Meningococcal Meningitis Case Reports in Nephrology |
| title | Bilateral Renal Cortical Necrosis in Meningococcal Meningitis |
| title_full | Bilateral Renal Cortical Necrosis in Meningococcal Meningitis |
| title_fullStr | Bilateral Renal Cortical Necrosis in Meningococcal Meningitis |
| title_full_unstemmed | Bilateral Renal Cortical Necrosis in Meningococcal Meningitis |
| title_short | Bilateral Renal Cortical Necrosis in Meningococcal Meningitis |
| title_sort | bilateral renal cortical necrosis in meningococcal meningitis |
| url | http://dx.doi.org/10.1155/2011/274341 |
| work_keys_str_mv | AT ckennedy bilateralrenalcorticalnecrosisinmeningococcalmeningitis AT skhilji bilateralrenalcorticalnecrosisinmeningococcalmeningitis AT adorman bilateralrenalcorticalnecrosisinmeningococcalmeningitis AT jwalshe bilateralrenalcorticalnecrosisinmeningococcalmeningitis |