M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity

M cells targeted H. pylori antigen SAM-FAdE displayed on bacterium-like particles induce protective immunity

Abstract Background Helicobacter pylori (H. pylori), a specific bacterium capable of surviving in the acidic environment of the stomach, has been recognized as a group of causative agents of gastric cancer. Therefore, the development of mucosal vaccines against H. pylori is expected to provide an im...

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Bibliographic Details
Main Authors: Furui Zhang, Jiale Chen, Zhen Zhang, Jing Wu, Yuliang Qu, Linhan Ni, Guolin Zhang, Kunmei Liu, Le Guo
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Nanobiotechnology
Subjects:
H. pylori
L. lactis
Bacterium-like particles
Surface display
M cells model
Online Access:https://doi.org/10.1186/s12951-025-03111-9
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