An ancient influenza genome from Switzerland allows deeper insights into host adaptation during the 1918 flu pandemic in Europe

An ancient influenza genome from Switzerland allows deeper insights into host adaptation during the 1918 flu pandemic in Europe

Abstract Background From 1918 to 1920, the largest influenza A virus (IAV) pandemic known to date spread globally causing between 20 to 100 million deaths. Historical records have captured critical aspects of the disease dynamics, such as the occurrence and severity of the pandemic waves. Yet, other...

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Main Authors: Christian Urban, Bram Vrancken, Livia V. Patrono, Ariane Düx, Mathilde Le Vu, Katarina L. Matthes, Nina Maria Burkhard-Koren, Navena Widulin, Thomas Schnalke, Sabina Carraro, Frank Rühli, Philippe Lemey, Kaspar Staub, Sébastien Calvignac-Spencer, Verena J. Schuenemann
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Biology
Subjects:
Ancient RNA
Influenza A virus
1918 flu pandemic
Ancient RNA method comparison
Online Access:https://doi.org/10.1186/s12915-025-02282-z
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https://doi.org/10.1186/s12915-025-02282-z

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