High-throughput methylation sequencing reveals novel biomarkers for the early detection of renal cell carcinoma

High-throughput methylation sequencing reveals novel biomarkers for the early detection of renal cell carcinoma

Abstract Purpose Renal cell carcinoma (RCC) is a common malignancy, with patients frequently diagnosed at an advanced stage due to the absence of sufficiently sensitive detection technologies, significantly compromising patient survival and quality of life. Advances in cell-free DNA (cfDNA) methylat...

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Main Authors: Wenhao Guo, Weiwu Chen, Jie Zhang, Mingzhe Li, Hongyuan Huang, Qian Wang, Xiaoyi Fei, Jian Huang, Tongning Zheng, Haobo Fan, Yunfei Wang, Hongcang Gu, Guoqing Ding, Yicheng Chen
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Cancer
Subjects:
Renal cell carcinoma
Cell-free DNA
DNA methylation
CpG islands
Liquid biopsy
Online Access:https://doi.org/10.1186/s12885-024-13380-6
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