Bilayer 3D co‐culture platform inducing the differentiation of normal fibroblasts into cancer‐associated fibroblast like cells: New in vitro source to obtain cancer‐associated fibroblasts

Abstract This study presents a novel in vitro bilayer 3D co‐culture platform designed to obtain cancer‐associated fibroblasts (CAFs)‐like cells. The platform consists of a bilayer hydrogel structure with a collagen/polyethylene glycol (PEG) hydrogel for fibroblasts as the upper layer and an alginate...

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Bibliographic Details
Main Authors: Yeon Ju Kim, Hyeon Song Lee, Dohyun Kim, Hwa Kyung Byun, Woong Sub Koom, Won‐Gun Koh
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Bioengineering & Translational Medicine
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Online Access:https://doi.org/10.1002/btm2.10708
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