Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness

This study evaluated the long-term toxicological and hygienic effects of the biological fertilizer “Yer Malhami” in white rats. The study used hygienic, toxicological, biochemical and statistical methods in accordance with the guidelines for environmental testing of bioinsecticides. A 12-month chron...

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Main Authors: Sherkuzieva Guzal, Salomova Feruza
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
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Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04031.pdf
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author Sherkuzieva Guzal
Salomova Feruza
author_facet Sherkuzieva Guzal
Salomova Feruza
author_sort Sherkuzieva Guzal
collection DOAJ
description This study evaluated the long-term toxicological and hygienic effects of the biological fertilizer “Yer Malhami” in white rats. The study used hygienic, toxicological, biochemical and statistical methods in accordance with the guidelines for environmental testing of bioinsecticides. A 12-month chronic experiment was conducted focusing on potential gonadotoxic, embryotropic and mutagenic effects. Rats were administered different doses of “Yer Malhami” and changes in body weight, reproductive cycles and cellular composition were observed. The results showed no significant disturbances in reproductive cycles or spermatogenesis, and chromosomal aberration tests showed no mutagenic effects. Although a slight decrease in fetal survival was observed at toxic doses, this was due to general toxicity rather than specific reproductive harm. The study concluded that Yer Malhami is safe for long-term use as a biofertilizer, with no adverse effects on reproductive or genetic health in the animals tested. Further studies are recommended to examine its safety in different species and environmental conditions.
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spelling doaj-art-83aa6da4d1694e36b9861ba9c0adea3c2025-02-05T10:42:42ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011510403110.1051/bioconf/202515104031bioconf_mblc2024_04031Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and EffectivenessSherkuzieva Guzal0Salomova Feruza1Tashkent Medical AcademyTashkent Medical AcademyThis study evaluated the long-term toxicological and hygienic effects of the biological fertilizer “Yer Malhami” in white rats. The study used hygienic, toxicological, biochemical and statistical methods in accordance with the guidelines for environmental testing of bioinsecticides. A 12-month chronic experiment was conducted focusing on potential gonadotoxic, embryotropic and mutagenic effects. Rats were administered different doses of “Yer Malhami” and changes in body weight, reproductive cycles and cellular composition were observed. The results showed no significant disturbances in reproductive cycles or spermatogenesis, and chromosomal aberration tests showed no mutagenic effects. Although a slight decrease in fetal survival was observed at toxic doses, this was due to general toxicity rather than specific reproductive harm. The study concluded that Yer Malhami is safe for long-term use as a biofertilizer, with no adverse effects on reproductive or genetic health in the animals tested. Further studies are recommended to examine its safety in different species and environmental conditions.https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04031.pdfhygienic standardizationdegree of toxicity and dangergonadotoxic effectembryotropic effectmutagenic effect
spellingShingle Sherkuzieva Guzal
Salomova Feruza
Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
BIO Web of Conferences
hygienic standardization
degree of toxicity and danger
gonadotoxic effect
embryotropic effect
mutagenic effect
title Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
title_full Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
title_fullStr Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
title_full_unstemmed Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
title_short Long-Term Effects of “Yer Malhami” Fertilizer: A Study on its Impact and Effectiveness
title_sort long term effects of yer malhami fertilizer a study on its impact and effectiveness
topic hygienic standardization
degree of toxicity and danger
gonadotoxic effect
embryotropic effect
mutagenic effect
url https://www.bio-conferences.org/articles/bioconf/pdf/2025/02/bioconf_mblc2024_04031.pdf
work_keys_str_mv AT sherkuzievaguzal longtermeffectsofyermalhamifertilizerastudyonitsimpactandeffectiveness
AT salomovaferuza longtermeffectsofyermalhamifertilizerastudyonitsimpactandeffectiveness