Giant transposons promote strain heterogeneity in a major fungal pathogen

Giant transposons promote strain heterogeneity in a major fungal pathogen

ABSTRACT Fungal infections are difficult to prevent and treat in large part due to strain heterogeneity, which confounds diagnostic predictability. Yet, the genetic mechanisms driving strain-to-strain variation remain poorly understood. Here, we determined the extent to which Starships—giant transpo...

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Bibliographic Details
Main Authors: Emile Gluck-Thaler, Adrian Forsythe, Charles Puerner, Cecilia Gutierrez-Perez, Jason E. Stajich, Daniel Croll, Robert A. Cramer, Aaron A. Vogan
Format: Article
Language:English
Published: American Society for Microbiology 2025-06-01
Series:mBio
Subjects:
transposable element
transposon
Aspergillosis
Aspergillus fumigatus
strain heterogeneity
secondary metabolism
Online Access:https://journals.asm.org/doi/10.1128/mbio.01092-25
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https://journals.asm.org/doi/10.1128/mbio.01092-25

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