Unusual Case of Hypereosinophilia in Hodgkin Lymphoma in a Nigerian Woman
Hodgkin lymphoma (HL) is characterized by Reed–Sternberg cells. Eosinophilia is an expected finding in patients with HL. However, there are few reports of hypereosinophilia in HL. We report a 45-year-old woman with fever, lymphadenopathy, and abdominal distention. Her complete blood count at present...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2024-01-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.0012 |
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| Summary: | Hodgkin lymphoma (HL) is characterized by Reed–Sternberg cells. Eosinophilia is an expected finding in patients with HL. However, there are few reports of hypereosinophilia in HL. We report a 45-year-old woman with fever, lymphadenopathy, and abdominal distention. Her complete blood count at presentation showed a total leukocyte count of 60 800 cells/mm3 with an eosinophil count of 46 000 cells/mm3. Lymph node biopsy revealed lymphocyte-rich HL, with eosinophil count dropping to 90 cells/mm3 after chemotherapy. Hypereosinophilia is unusual and needs to be extensively investigated. In HL, hypereosinophilia is thought to occur from cytokine secretion by Reed–Steinberg cells. |
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| ISSN: | 2767-7664 |