Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods

Xanthione is a sulfated polycyclic aromatic hydrocarbon which exhibits unique anti-Kasha properties and substantial sensitivity to its medium. Due to this sensitivity however, this makes xanthione-based systems very difficult to simulate. Further, xanthione’s is understood to be come more photostabl...

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Main Authors: Anjay Manian, Zifei Chen, Rohan J. Hudson, Salvy P. Russo
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/29/23/5609
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author Anjay Manian
Zifei Chen
Rohan J. Hudson
Salvy P. Russo
author_facet Anjay Manian
Zifei Chen
Rohan J. Hudson
Salvy P. Russo
author_sort Anjay Manian
collection DOAJ
description Xanthione is a sulfated polycyclic aromatic hydrocarbon which exhibits unique anti-Kasha properties and substantial sensitivity to its medium. Due to this sensitivity however, this makes xanthione-based systems very difficult to simulate. Further, xanthione’s is understood to be come more photostable in the presence of a highly polar medium, however whether these photophysical properties could be taken advantage of for certain applications remains to be seen. In clarifying long-held beliefs of specific solvent effects, we apply a rigorous theoretical solvent analysis in both implicit and explicit solvent mediums to elucidate a more complete description of solvent polarity sensitivity in xanthione using both quantum chemical and molecular dynamics techniques. Not only was it found that explicit solvation methods are vital in an accurate description of the system, only a handful of explicit solvent molecules in the simulation are required to yield an appropriate electronic description. This short work is vital to devising future applications for xanthione-based and other quantum technologies, and is an important foundation stone on this journey.
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spelling doaj-art-830e601c1c5b47ffa1cb15d083b48bbe2025-08-20T02:38:50ZengMDPI AGMolecules1420-30492024-11-012923560910.3390/molecules29235609Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent MethodsAnjay Manian0Zifei Chen1Rohan J. Hudson2Salvy P. Russo3ARC Centre of Excellence in Exciton Science, School of Science, RMIT University, Melbourne 3000, AustraliaARC Centre of Excellence in Exciton Science, School of Science, RMIT University, Melbourne 3000, AustraliaARC Centre of Excellence in Exciton Science, School of Chemistry, University of Melbourne, Parkville 3010, AustraliaARC Centre of Excellence in Exciton Science, School of Science, RMIT University, Melbourne 3000, AustraliaXanthione is a sulfated polycyclic aromatic hydrocarbon which exhibits unique anti-Kasha properties and substantial sensitivity to its medium. Due to this sensitivity however, this makes xanthione-based systems very difficult to simulate. Further, xanthione’s is understood to be come more photostable in the presence of a highly polar medium, however whether these photophysical properties could be taken advantage of for certain applications remains to be seen. In clarifying long-held beliefs of specific solvent effects, we apply a rigorous theoretical solvent analysis in both implicit and explicit solvent mediums to elucidate a more complete description of solvent polarity sensitivity in xanthione using both quantum chemical and molecular dynamics techniques. Not only was it found that explicit solvation methods are vital in an accurate description of the system, only a handful of explicit solvent molecules in the simulation are required to yield an appropriate electronic description. This short work is vital to devising future applications for xanthione-based and other quantum technologies, and is an important foundation stone on this journey.https://www.mdpi.com/1420-3049/29/23/5609xanthionesolvent effectsexplicit solvationDFTMRCIMD
spellingShingle Anjay Manian
Zifei Chen
Rohan J. Hudson
Salvy P. Russo
Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
Molecules
xanthione
solvent effects
explicit solvation
DFT
MRCI
MD
title Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
title_full Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
title_fullStr Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
title_full_unstemmed Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
title_short Simulation of Solvatochromic Phenomena in Xanthione Using Explicit Solvent Methods
title_sort simulation of solvatochromic phenomena in xanthione using explicit solvent methods
topic xanthione
solvent effects
explicit solvation
DFT
MRCI
MD
url https://www.mdpi.com/1420-3049/29/23/5609
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AT salvyprusso simulationofsolvatochromicphenomenainxanthioneusingexplicitsolventmethods