Cathepsin-D and outcomes in peripartum cardiomyopathy: Results from IPAC

Cathepsin-D and outcomes in peripartum cardiomyopathy: Results from IPAC

Objective: Evaluate the relationship of cathepsin-D (CD) on disease severity and clinical outcomes for women with peripartum cardiomyopathy. Background: Cathepsin-D is a protease released during oxidative stress that cleaves prolactin (PRL) generating a 16 kDa fragment that is pro-apoptotic, anti-an...

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Bibliographic Details
Main Authors: Vincenzo B. Polsinelli, Karen Hanley-Yanez, Charles F. McTiernan, Kalgi Modi, Jennifer Haythe, Hal Skopicki, Uri Elkayam, Leslie T. Cooper, Jr, James D. Fett, Dennis M. McNamara
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:American Heart Journal Plus
Subjects:
Cardiomyopathies
Heart failure
Peripartum cardiomyopathy
Pregnancy
Online Access:http://www.sciencedirect.com/science/article/pii/S2666602224001320
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