ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression

ACVR2A facilitates trophoblast cell invasion through TCF7/c-JUN pathway in pre-eclampsia progression

Pre-eclampsia (PE) is a serious pregnancy disorder linked to genetic factors, particularly the ACVR2A gene, which encodes a receptor involved in the activin signaling pathway and plays a critical role in reproductive processes. Transcriptomic data analysis and experimental verification confirmed a d...

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Bibliographic Details
Main Authors: Shujing Yang, Huanyao Liu, Jieshi Hu, Binjun Chen, Wanlu An, Xuwen Song, Yi Yang, Fang He
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
pre-eclampsia
ACVR2A
HTR8/SVneo
JAR
TCF7
c-JUN
Online Access:https://elifesciences.org/articles/101236
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