Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application

Transcriptomic profiling of cytomegalovirus infection in cardiac transplantation: proof-of-concept for a new strategy in tissue markers application

BackgroundCytomegalovirus (CMV) infection is a relevant threat to heart-transplanted patients during the first year after surgery, leading to increased morbidity and, in some cases, mortality. This proof-of-concept study aims to assess the transcriptomic profile of CMV infection in cardiac transplan...

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Main Authors: Ilaria Barison, Diego Perazzolo, Chiara Castellani, Alessia Giarraputo, Elisabetta Rossi, Luca Vedovelli, Sonia Anna Minuzzo, Chiara Tessari, Nicola Pradegan, Giuseppe Toscano, Francesco Tona, Cristina Basso, Gino Gerosa, Susanna Mandruzzato, Davide Abate, Dario Gregori, Annalisa Angelini, Marny Fedrigo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
cytomegalovirus
heart transplant
rejection
transcriptomic profiling mRNA
miRNA
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581151/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1581151/full

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