Statistical identification of cell type-specific spatially variable genes in spatial transcriptomics
Abstract An essential task in spatial transcriptomics is identifying spatially variable genes (SVGs). Here, we present Celina, a statistical method for systematically detecting cell type-specific SVGs (ct-SVGs)—a subset of SVGs exhibiting distinct spatial expression patterns within specific cell typ...
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Main Authors: | Lulu Shang, Peijun Wu, Xiang Zhou |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-025-56280-4 |
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