Statistical identification of cell type-specific spatially variable genes in spatial transcriptomics

Abstract An essential task in spatial transcriptomics is identifying spatially variable genes (SVGs). Here, we present Celina, a statistical method for systematically detecting cell type-specific SVGs (ct-SVGs)—a subset of SVGs exhibiting distinct spatial expression patterns within specific cell typ...

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Bibliographic Details
Main Authors: Lulu Shang, Peijun Wu, Xiang Zhou
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56280-4
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