Primary Breast Angiosarcoma: Avoiding a Common Trap

Background. Primary breast angiosarcoma is a rare entity. Case. Initial diagnosis was a benign hemangioma at core biopsy. Wide local excision was performed, with positive margins. Pathology after surgery reported a moderately differentiated angiosarcoma. Tumor was finally treated using mastectomy...

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Main Authors: Christine Desbiens, Jean-Charles Hogue, Yves Lévesque
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2011/517047
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author Christine Desbiens
Jean-Charles Hogue
Yves Lévesque
author_facet Christine Desbiens
Jean-Charles Hogue
Yves Lévesque
author_sort Christine Desbiens
collection DOAJ
description Background. Primary breast angiosarcoma is a rare entity. Case. Initial diagnosis was a benign hemangioma at core biopsy. Wide local excision was performed, with positive margins. Pathology after surgery reported a moderately differentiated angiosarcoma. Tumor was finally treated using mastectomy and radiations. She developed a second angiosarcoma in contralateral breast, with an initial diagnosis on core biopsy of an atypical vascular lesion and was again treated using mastectomy and radiations. She developed bones and lung metastases. Conclusion. Primary breast angiosarcoma is a rare entity often difficult to diagnose on core biopsy, and a benign differential diagnosis is frequent. A highly vascular breast mass should always be considered malignant until proven otherwise. Surgical treatment seems to be the best course of action. There is a lack of data proving efficacy of adjuvant chemotherapy and radiation therapy.
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spelling doaj-art-81d5f80069b948efa6b9ccca59fd6c382025-02-03T01:32:15ZengWileyCase Reports in Oncological Medicine2090-67062090-67142011-01-01201110.1155/2011/517047517047Primary Breast Angiosarcoma: Avoiding a Common TrapChristine Desbiens0Jean-Charles Hogue1Yves Lévesque2Centre des Maladies du Sein Deschênes-Fabia, Hôpital du Saint-Sacrement, CHA Universitaire de Québec, 1050 chemin Sainte-Foy, Québec City, QC, G1S 4L8, CanadaCentre des Maladies du Sein Deschênes-Fabia, Hôpital du Saint-Sacrement, CHA Universitaire de Québec, 1050 chemin Sainte-Foy, Québec City, QC, G1S 4L8, CanadaHôtel-Dieu d'Arthabaska, 5 Rue des Hospitalières, Victoriaville, Québec City, QC, G6P 6N2, CanadaBackground. Primary breast angiosarcoma is a rare entity. Case. Initial diagnosis was a benign hemangioma at core biopsy. Wide local excision was performed, with positive margins. Pathology after surgery reported a moderately differentiated angiosarcoma. Tumor was finally treated using mastectomy and radiations. She developed a second angiosarcoma in contralateral breast, with an initial diagnosis on core biopsy of an atypical vascular lesion and was again treated using mastectomy and radiations. She developed bones and lung metastases. Conclusion. Primary breast angiosarcoma is a rare entity often difficult to diagnose on core biopsy, and a benign differential diagnosis is frequent. A highly vascular breast mass should always be considered malignant until proven otherwise. Surgical treatment seems to be the best course of action. There is a lack of data proving efficacy of adjuvant chemotherapy and radiation therapy.http://dx.doi.org/10.1155/2011/517047
spellingShingle Christine Desbiens
Jean-Charles Hogue
Yves Lévesque
Primary Breast Angiosarcoma: Avoiding a Common Trap
Case Reports in Oncological Medicine
title Primary Breast Angiosarcoma: Avoiding a Common Trap
title_full Primary Breast Angiosarcoma: Avoiding a Common Trap
title_fullStr Primary Breast Angiosarcoma: Avoiding a Common Trap
title_full_unstemmed Primary Breast Angiosarcoma: Avoiding a Common Trap
title_short Primary Breast Angiosarcoma: Avoiding a Common Trap
title_sort primary breast angiosarcoma avoiding a common trap
url http://dx.doi.org/10.1155/2011/517047
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