Microspatial Heterogeneities and the Absence of Postmortem Contamination in Alzheimer’s Disease Brain Microbiota: An Alzheimer’s Pathobiome Initiative (AlzPI) Study

Microspatial Heterogeneities and the Absence of Postmortem Contamination in Alzheimer’s Disease Brain Microbiota: An Alzheimer’s Pathobiome Initiative (AlzPI) Study

The discovery of profound differences in the brain microbiota of Alzheimer’s disease (AD) patients and age-matched controls (AMCs) raised questions of postmortem contamination and bacterial transport processes which could be informed by microspatial heterogeneities. We performed semiquantitative spe...

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Bibliographic Details
Main Authors: Myat N. Thwe, Yves Moné, Bhaswati Sen, Samuel Czerski, Ahmed Azad, Joshua P. Earl, Donald C. Hall, Garth D. Ehrlich
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Microorganisms
Subjects:
Alzheimer’s disease
microbiome
pathobiome
Dirichlet-multinomial modeling
Bayesian statistics
contamination
Online Access:https://www.mdpi.com/2076-2607/13/4/807
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