Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?

Background. Gastrinoma-positive lymph nodes and failed localization of the primary tumor during surgical exploration are described. Specialists suppose that these lymph nodes are metastases rather than a primary gastrinoma. Methods. Case report with a five-year long-term followup. A 60-year-old pati...

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Main Authors: Bernd Jaenigen, Gian Kayser, Berthold Steinke, Oliver Thomusch
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2009/762791
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author Bernd Jaenigen
Gian Kayser
Berthold Steinke
Oliver Thomusch
author_facet Bernd Jaenigen
Gian Kayser
Berthold Steinke
Oliver Thomusch
author_sort Bernd Jaenigen
collection DOAJ
description Background. Gastrinoma-positive lymph nodes and failed localization of the primary tumor during surgical exploration are described. Specialists suppose that these lymph nodes are metastases rather than a primary gastrinoma. Methods. Case report with a five-year long-term followup. A 60-year-old patient with an confirmed gastrinoma was treated in our department. All preoperative evaluations including somatostatin-receptor-scintigraphy and F-Dopa PET failed to localize the gastrinoma. Explorative laparotomy revealed a gastrinoma in two peripancreatic lymph nodes. Despite extensive intraoperative exploration, no primary gastrinoma could be detected in typical localization. Results. Over a period of 5 years, the patient's gastrin level stayed in the normal range and the patient seems to be completely cured. Conclusion. A prophylactic partial pancreatoduodenectomy is not indicated to avoid recurrence, since complete biochemical cure by local resection of the lymph node gastrinoma is possible.
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institution Kabale University
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spelling doaj-art-81a9d89c1b13419aa687d0d85f3a34672025-02-03T01:10:47ZengWileyCase Reports in Medicine1687-96271687-96352009-01-01200910.1155/2009/762791762791Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?Bernd Jaenigen0Gian Kayser1Berthold Steinke2Oliver Thomusch3Department of General and Visceral Surgery, Albert-Ludwigs University of Freiburg, 79106 Freiburg, GermanyInstitute of Pathology, Albert-Ludwigs University of Freiburg, 79106 Freiburg, GermanyDepartment of Internal Medicine, County Hospital Rottweil, 78628 Rottweil, GermanyDepartment of General and Visceral Surgery, Albert-Ludwigs University of Freiburg, 79106 Freiburg, GermanyBackground. Gastrinoma-positive lymph nodes and failed localization of the primary tumor during surgical exploration are described. Specialists suppose that these lymph nodes are metastases rather than a primary gastrinoma. Methods. Case report with a five-year long-term followup. A 60-year-old patient with an confirmed gastrinoma was treated in our department. All preoperative evaluations including somatostatin-receptor-scintigraphy and F-Dopa PET failed to localize the gastrinoma. Explorative laparotomy revealed a gastrinoma in two peripancreatic lymph nodes. Despite extensive intraoperative exploration, no primary gastrinoma could be detected in typical localization. Results. Over a period of 5 years, the patient's gastrin level stayed in the normal range and the patient seems to be completely cured. Conclusion. A prophylactic partial pancreatoduodenectomy is not indicated to avoid recurrence, since complete biochemical cure by local resection of the lymph node gastrinoma is possible.http://dx.doi.org/10.1155/2009/762791
spellingShingle Bernd Jaenigen
Gian Kayser
Berthold Steinke
Oliver Thomusch
Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
Case Reports in Medicine
title Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
title_full Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
title_fullStr Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
title_full_unstemmed Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
title_short Five-Year Long-Term Followup of a Primary Lymph node Gastrinoma: Is a Pancreaticoduodenectomy Justified?
title_sort five year long term followup of a primary lymph node gastrinoma is a pancreaticoduodenectomy justified
url http://dx.doi.org/10.1155/2009/762791
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AT bertholdsteinke fiveyearlongtermfollowupofaprimarylymphnodegastrinomaisapancreaticoduodenectomyjustified
AT oliverthomusch fiveyearlongtermfollowupofaprimarylymphnodegastrinomaisapancreaticoduodenectomyjustified