Transcutaneous auricular vagus nerve stimulation regulates gut microbiota mediated peripheral inflammation and metabolic disorders to suppress depressive-like behaviors in CUMS rats

Transcutaneous auricular vagus nerve stimulation regulates gut microbiota mediated peripheral inflammation and metabolic disorders to suppress depressive-like behaviors in CUMS rats

BackgroundDepression is a common mental disorder, and the changes of intestinal microflora and peripheral plasma metabolites can affect the gut-brain axis through vagus nerve, leading to the occurrence, and progress of the disease. Transcutaneous auricular vagus nerve stimulation (taVNS) has been pr...

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Bibliographic Details
Main Authors: Xinjiang Zhang, Xun He, Yanan Zhao, Qi Zou, Yulong Liang, Jinling Zhang, Bowen Feng, Peijing Rong, Yu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
depression
gut microbiota
metabolomics
brain-gut axis
transcutaneous auricular vagus nerve stimulation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1576686/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1576686/full

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