Actively protective combinatorial analysis: A scalable novel method for detecting variants that contribute to reduced disease prevalence in high-risk individuals

We present a novel method for routinely identifying disease resilience associations that offers powerful insights for the discovery of a new class of disease protective targets. We show how this can be used to identify mechanisms in the background of normal cellular biology that work to slow or stop...

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Bibliographic Details
Main Authors: J Sardell, S Das, K Taylor, C Stubberfield, A Malinowski, M Strivens, S Gardner
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Artificial Intelligence in the Life Sciences
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667318525000017
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