Inhibition of Histone Methyltransferase, Histone Deacetylase, and β-Catenin Synergistically Enhance the Cardiac Potential of Bone Marrow Cells

Previously, we reported that treatment with the G9a histone methyltransferase inhibitor BIX01294 causes bone marrow mesenchymal stem cells (MSCs) to exhibit a cardiocompetent phenotype, as indicated by the induction of the precardiac markers Mesp1 and brachyury. Here, we report that combining the hi...

Full description

Saved in:
Bibliographic Details
Main Authors: Jinpu Yang, Keerat Kaur, John G. Edwards, Carol A. Eisenberg, Leonard M. Eisenberg
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/3464953
Tags: Add Tag
No Tags, Be the first to tag this record!