Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes
Electrochemical biosensors are essential for health monitors to help in diagnosis and detection of diseases. Enzyme adsorptions on biosensor electrodes and direct electron transfer between them have been recognized as key factors to affect biosensor performance. TiO2 has a good protein adsorption ab...
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| Format: | Article |
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Wiley
2014-01-01
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| Series: | Advances in Materials Science and Engineering |
| Online Access: | http://dx.doi.org/10.1155/2014/965821 |
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| author | M. S. H. Al-Furjan Kui Cheng Wenjian Weng |
| author_facet | M. S. H. Al-Furjan Kui Cheng Wenjian Weng |
| author_sort | M. S. H. Al-Furjan |
| collection | DOAJ |
| description | Electrochemical biosensors are essential for health monitors to help in diagnosis and detection of diseases. Enzyme adsorptions on biosensor electrodes and direct electron transfer between them have been recognized as key factors to affect biosensor performance. TiO2 has a good protein adsorption ability and facilitates having more enzyme adsorption and better electron transfer. In this work, Mg ions are introduced into TiO2 nanodots in order to further improve electrode performance because Mg ions are considered to have good affinity with proteins or enzymes. Mg doped TiO2 nanodots on Ti substrates were prepared by spin-coating and calcining. The effects of Mg doping on the nanodots morphology and performance of the electrodes were investigated. The density and size of TiO2 nanodots were obviously changed with Mg doping. The sensitivity of 2% Mg doped TiO2 nanodots based biosensor electrode increased to 1377.64 from 897.8 µA mM−1 cm−2 and its KMapp decreases to 0.83 from 1.27 mM, implying that the enzyme achieves higher catalytic efficiency due to better affinity of the enzyme with the Mg doped TiO2. The present work could provide an alternative to improve biosensor performances. |
| format | Article |
| id | doaj-art-80a8b8dc5b65408b9e1418ccc4ff171c |
| institution | Kabale University |
| issn | 1687-8434 1687-8442 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Materials Science and Engineering |
| spelling | doaj-art-80a8b8dc5b65408b9e1418ccc4ff171c2025-02-03T06:10:48ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422014-01-01201410.1155/2014/965821965821Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor ElectrodesM. S. H. Al-Furjan0Kui Cheng1Wenjian Weng2State Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Department of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Department of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaState Key Laboratory of Silicon Materials, Cyrus Tang Center for Sensor Materials and Applications, Department of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, ChinaElectrochemical biosensors are essential for health monitors to help in diagnosis and detection of diseases. Enzyme adsorptions on biosensor electrodes and direct electron transfer between them have been recognized as key factors to affect biosensor performance. TiO2 has a good protein adsorption ability and facilitates having more enzyme adsorption and better electron transfer. In this work, Mg ions are introduced into TiO2 nanodots in order to further improve electrode performance because Mg ions are considered to have good affinity with proteins or enzymes. Mg doped TiO2 nanodots on Ti substrates were prepared by spin-coating and calcining. The effects of Mg doping on the nanodots morphology and performance of the electrodes were investigated. The density and size of TiO2 nanodots were obviously changed with Mg doping. The sensitivity of 2% Mg doped TiO2 nanodots based biosensor electrode increased to 1377.64 from 897.8 µA mM−1 cm−2 and its KMapp decreases to 0.83 from 1.27 mM, implying that the enzyme achieves higher catalytic efficiency due to better affinity of the enzyme with the Mg doped TiO2. The present work could provide an alternative to improve biosensor performances.http://dx.doi.org/10.1155/2014/965821 |
| spellingShingle | M. S. H. Al-Furjan Kui Cheng Wenjian Weng Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes Advances in Materials Science and Engineering |
| title | Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes |
| title_full | Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes |
| title_fullStr | Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes |
| title_full_unstemmed | Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes |
| title_short | Influences of Mg Doping on the Electrochemical Performance of TiO2 Nanodots Based Biosensor Electrodes |
| title_sort | influences of mg doping on the electrochemical performance of tio2 nanodots based biosensor electrodes |
| url | http://dx.doi.org/10.1155/2014/965821 |
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