Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study
Objective: To explore the underlying causes of death among vaccinated COVID-19 patients. Methods: The medical record of COVID-19 patients admitted to the main COVID-19 referral center in southeast Iran from January to March 2022 was investigated. Then, risk factors for mortality were statistically a...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Journal of Acute Disease |
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| Online Access: | https://journals.lww.com/10.4103/jad.jad_88_24 |
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| _version_ | 1832087230858919936 |
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| author | Hossein Lajmiri Nioosha Ahmadi Saeedeh Ebrahimi Hadi Razavi Nikoo Mehrdad Farrokhnia Elham Heidari Elham Mousavi |
| author_facet | Hossein Lajmiri Nioosha Ahmadi Saeedeh Ebrahimi Hadi Razavi Nikoo Mehrdad Farrokhnia Elham Heidari Elham Mousavi |
| author_sort | Hossein Lajmiri |
| collection | DOAJ |
| description | Objective:
To explore the underlying causes of death among vaccinated COVID-19 patients.
Methods:
The medical record of COVID-19 patients admitted to the main COVID-19 referral center in southeast Iran from January to March 2022 was investigated. Then, risk factors for mortality were statistically assessed.
Results:
92 patients were included, with 50 in infectious disease ward and 42 in ICU ward. In total, 37% of patients succumbed to COVID-19. The median age of those who died was 69.9 years. Dementia and genitourinary system-related diseases was associated with an increased risk of death [6.00 (95% CI: 1.14-31.66) and 4.93 (95% CI: 1.80-13.52)]. Furthermore, the elevated levels of white blood cells, neutrophils, lactate dehydrogenase, blood urea nitrogen, and creatinine were associated with an increased risk of death by 4.93 (95% CI: 1.82-13.36), 16.57 (95% CI: 2.10-131.31), 3.23 (95% CI: 1.15-9.03), 4.48 (95% CI: 1.78-11.31), and 4.27 (95% CI: 1.49-12.22), respectively.
Conclusions:
Despite receiving the SARS-CoV-2 vaccine, individuals who suffer from dementia and genitourinary system-related diseases are at risk of death with new strains of SARS-CoV-2 infection. Furthermore, the increase of white blood cell, neutrophils, lactate dehydrogenase, blood urea nitrogen, and creatinine in patients’ blood can be considered as warning indicators of disease progression and death. |
| format | Article |
| id | doaj-art-809457bc00a54f1caf270426e91e304b |
| institution | Kabale University |
| issn | 2221-6189 2589-5516 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj-art-809457bc00a54f1caf270426e91e304b2025-02-06T05:53:38ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892589-55162024-12-0113619920710.4103/jad.jad_88_24Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective studyHossein LajmiriNioosha AhmadiSaeedeh EbrahimiHadi Razavi NikooMehrdad FarrokhniaElham HeidariElham MousaviObjective: To explore the underlying causes of death among vaccinated COVID-19 patients. Methods: The medical record of COVID-19 patients admitted to the main COVID-19 referral center in southeast Iran from January to March 2022 was investigated. Then, risk factors for mortality were statistically assessed. Results: 92 patients were included, with 50 in infectious disease ward and 42 in ICU ward. In total, 37% of patients succumbed to COVID-19. The median age of those who died was 69.9 years. Dementia and genitourinary system-related diseases was associated with an increased risk of death [6.00 (95% CI: 1.14-31.66) and 4.93 (95% CI: 1.80-13.52)]. Furthermore, the elevated levels of white blood cells, neutrophils, lactate dehydrogenase, blood urea nitrogen, and creatinine were associated with an increased risk of death by 4.93 (95% CI: 1.82-13.36), 16.57 (95% CI: 2.10-131.31), 3.23 (95% CI: 1.15-9.03), 4.48 (95% CI: 1.78-11.31), and 4.27 (95% CI: 1.49-12.22), respectively. Conclusions: Despite receiving the SARS-CoV-2 vaccine, individuals who suffer from dementia and genitourinary system-related diseases are at risk of death with new strains of SARS-CoV-2 infection. Furthermore, the increase of white blood cell, neutrophils, lactate dehydrogenase, blood urea nitrogen, and creatinine in patients’ blood can be considered as warning indicators of disease progression and death.https://journals.lww.com/10.4103/jad.jad_88_24covid-19mortalityrisk factorscomorbiditieslaboratory parameters |
| spellingShingle | Hossein Lajmiri Nioosha Ahmadi Saeedeh Ebrahimi Hadi Razavi Nikoo Mehrdad Farrokhnia Elham Heidari Elham Mousavi Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study Journal of Acute Disease covid-19 mortality risk factors comorbidities laboratory parameters |
| title | Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study |
| title_full | Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study |
| title_fullStr | Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study |
| title_full_unstemmed | Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study |
| title_short | Risk factors associated with mortality among vaccinated COVID-19 patients: A retrospective study |
| title_sort | risk factors associated with mortality among vaccinated covid 19 patients a retrospective study |
| topic | covid-19 mortality risk factors comorbidities laboratory parameters |
| url | https://journals.lww.com/10.4103/jad.jad_88_24 |
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