Multiparametric physicochemical analysis of a type 1 collagen 3D cell culture model using light and electron microscopy and mass spectrometry imaging

Abstract Three-dimensional cell culture systems underpin cell-based technologies ranging from tissue scaffolds for regenerative medicine to tumor models and organoids for drug screening. However, to realise the full potential of these technologies requires analytical methods able to capture the dive...

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Bibliographic Details
Main Authors: Camilla Dondi, Dimitrios Tsikritsis, Jean-Luc Vorng, Gina Greenidge, Ibolya E. Kepiro, Natalie A. Belsey, Greg McMahon, Ian S. Gilmore, Maxim G. Ryadnov, Michael Shaw
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-93700-3
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