Dual-functional titanium implants via polydopamine-mediated lithium and copper co-incorporation: synergistic enhancement of osseointegration and antibacterial efficacy

Dual-functional titanium implants via polydopamine-mediated lithium and copper co-incorporation: synergistic enhancement of osseointegration and antibacterial efficacy

IntroductionOrthopedic implant failure due to inadequate osseointegration and infection remains a critical challenge. To address this, we engineered a polydopamine (PDA)-mediated dual-functional platform for lithium (Li+) and copper (Cu2+) co-incorporation on titanium alloy (Ti6Al4V) implants, aimin...

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Bibliographic Details
Main Authors: Jun Li, Bo Jiang, Liu Yang, Pu Zhang, Jingwen Wu, Yalan Yang, Yan Yang, Guiling Wang, Jie Chen, Ling Zhang, Shiqin Huang, Lingli Zhang, En Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Ti6Al4V
surface modification
metal ions
antibacterial
osseointegration
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1593545/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1593545/full

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