Inhibition of the production of mediators of inflammation by corticosteroids is a glucocorticoid receptor-mediated process
In order to find an explanation for corticosteroid resistance we assessed whether inhibition by dexamethasone (DEX) of the stimulated production of TNF-∝, IL-6, PGE2 and LTB4 by peripheral blood mononuclear cells (MNC) depends on binding to the glucocorticoid receptor (GR), and whether it is determi...
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Main Authors: | G. S. Madretsma, A. P. M. van Dijk, C. J. A. M. Tak, J. H. P. Wilson, F. J. Zijlstra |
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Format: | Article |
Language: | English |
Published: |
Wiley
1996-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935196000166 |
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