Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering

Transcriptome signature in the blood of neuromyelitis optica spectrum disorder under steroid tapering

BackgroundThe advent of biologics has significantly transformed treatment strategies for neuromyelitis optica spectrum disorder (NMOSD). However, there are no biomarkers that predict relapses associated with steroid tapering; therefore, it is critical to identify potential indicators of disease acti...

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Main Authors: Ryohei Yamamura, Makoto Kinoshita, Yoshiaki Yasumizu, Tomohiro Yata, Keigo Kihara, Daisuke Motooka, Naoyuki Shiraishi, Yasuko Sugiyama, Shohei Beppu, Hisashi Murata, Naoshi Koizumi, Itsuki Sano, Toru Koda, Tatsusada Okuno, Hideki Mochizuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
NMOSD
steroid
transcriptome signature
IL-10
interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1508977/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1508977/full

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