Mixed-dimensional fluid–structure interaction simulations reveal key mechanisms of cerebrospinal fluid dynamics in the spinal canal

Abstract Cerebrospinal flow dynamics (CSF) plays a critical role in structural disorders of the central nervous system (CNS) and in the design of effective procedures for intrathecal drug delivery. Medical imaging techniques have only partially characterized CSF dynamics. Computational models have t...

Full description

Saved in:
Bibliographic Details
Main Authors: Deshik Reddy Putluru, Adrian Buganza Tepole, Hector Gomez
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-025-00691-4
Tags: Add Tag
No Tags, Be the first to tag this record!