Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes
Propionibacterium acnes is the main organism that leads to acne. P. acnes belongs to a group of gram-positive bacteria. Antibiotics can be used to relieve acne, but they could lead bacteria to accumulate resistance. As a result, a safe and cost-effective treatment strategy is required. An instance i...
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EDP Sciences
2025-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2025/07/bioconf_icfaes24_01007.pdf |
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| author | Irwan Irwan Pohan Napitupulu Nurhasanah Amri MC Ulil Adawiyah Rabiyatul Akram Habibul Nursafiah Nursafiah Nurliza Eli |
| author_facet | Irwan Irwan Pohan Napitupulu Nurhasanah Amri MC Ulil Adawiyah Rabiyatul Akram Habibul Nursafiah Nursafiah Nurliza Eli |
| author_sort | Irwan Irwan |
| collection | DOAJ |
| description | Propionibacterium acnes is the main organism that leads to acne. P. acnes belongs to a group of gram-positive bacteria. Antibiotics can be used to relieve acne, but they could lead bacteria to accumulate resistance. As a result, a safe and cost-effective treatment strategy is required. An instance is using Acrostichum aureum Linn leaves, which contain several bioactive chemicals that function as antibacterial. This study aims to identify the bioactive compounds and antibacterial activity of the methanolic extract of Acrostichum aureum Linn against Propionibacterium acnes. The study started with extraction (maceration method) with methanol solvent for 3 days, followed by phytochemical tests to identify bioactive compounds, and an antibacterial activity test using the disc diffusion method. Phytochemical tests on the methanol extract of Acrostichum aureum Linn leaves revealed five bioactive compounds consisted of alkaloids, flavonoids, tannins, steroids, and saponins. Antibacterial tests against Propionibacterium acnes exhibited no inhibition zone at concentrations of extract from 5% to 75%. However, at 100% concentration, indicating strong inhibition of P. acnes growth (diameter zone is 16 mm). Based on the research, it is conceivable to conclude that the extract has strong antibacterial activity against Propionibacterium acnes at a concentration of 100%. |
| format | Article |
| id | doaj-art-801b3516bcbc4f8bafde7f6d01ed34aa |
| institution | Kabale University |
| issn | 2117-4458 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj-art-801b3516bcbc4f8bafde7f6d01ed34aa2025-02-05T10:43:32ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011560100710.1051/bioconf/202515601007bioconf_icfaes24_01007Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnesIrwan Irwan0Pohan Napitupulu Nurhasanah1Amri MC Ulil2Adawiyah Rabiyatul3Akram Habibul4Nursafiah Nursafiah5Nurliza Eli6Department of Marine Sciences, Faculty of Marine and Fisheries, Universitas Syiah KualaDepartment of Marine Sciences, Faculty of Marine and Fisheries, Universitas Syiah KualaDepartment of Marine Sciences, Faculty of Marine and Fisheries, Universitas Syiah KualaDepartment of Biology Education, Faculty of Teacher and Education, PSDKU Universitas Syiah KualaDepartment of Biology Education, Faculty of Education and Teacher Training, Gunung Leuser UniversityDepartment of Biology Education, Faculty of Education and Teacher Training, Gunung Leuser UniversityDepartment of Indonesian Languange Education, Faculty of Teacher Training and Education, Serambi Mekkah UniversityPropionibacterium acnes is the main organism that leads to acne. P. acnes belongs to a group of gram-positive bacteria. Antibiotics can be used to relieve acne, but they could lead bacteria to accumulate resistance. As a result, a safe and cost-effective treatment strategy is required. An instance is using Acrostichum aureum Linn leaves, which contain several bioactive chemicals that function as antibacterial. This study aims to identify the bioactive compounds and antibacterial activity of the methanolic extract of Acrostichum aureum Linn against Propionibacterium acnes. The study started with extraction (maceration method) with methanol solvent for 3 days, followed by phytochemical tests to identify bioactive compounds, and an antibacterial activity test using the disc diffusion method. Phytochemical tests on the methanol extract of Acrostichum aureum Linn leaves revealed five bioactive compounds consisted of alkaloids, flavonoids, tannins, steroids, and saponins. Antibacterial tests against Propionibacterium acnes exhibited no inhibition zone at concentrations of extract from 5% to 75%. However, at 100% concentration, indicating strong inhibition of P. acnes growth (diameter zone is 16 mm). Based on the research, it is conceivable to conclude that the extract has strong antibacterial activity against Propionibacterium acnes at a concentration of 100%.https://www.bio-conferences.org/articles/bioconf/pdf/2025/07/bioconf_icfaes24_01007.pdf |
| spellingShingle | Irwan Irwan Pohan Napitupulu Nurhasanah Amri MC Ulil Adawiyah Rabiyatul Akram Habibul Nursafiah Nursafiah Nurliza Eli Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes BIO Web of Conferences |
| title | Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes |
| title_full | Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes |
| title_fullStr | Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes |
| title_full_unstemmed | Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes |
| title_short | Antibacterial activity of methanolic extract of Acrostichum Aureum Linn leaves against Propionibacterium acnes |
| title_sort | antibacterial activity of methanolic extract of acrostichum aureum linn leaves against propionibacterium acnes |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2025/07/bioconf_icfaes24_01007.pdf |
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