Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota

Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota

Antibiotic resistance is a global public health challenge. The gut microbiota serves as a reservoir for antibiotic resistance genes (ARGs), facilitating their transfer between bacteria. With the rising incidence of major depressive disorders (MDD), antidepressant prescriptions have surged. Previous...

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Bibliographic Details
Main Authors: Pengbo Ding, Ji Lu, Tong Lei, Yinan Guo, Baoli Zhu, Yong Zhao, Yue Wang, Jan Engelstädter, Mark A. Schembri, Jianhua Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Antidepressants
antibiotic resistance
horizontal gene transfer
conjugation
plasmid
gut microbiota
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2514138
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2514138

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