Does intermittent nutrition enterally normalise hormonal and metabolic responses to feeding in critically ill adults? A protocol for the DINE-Normal proof-of-concept randomised parallel-group study

Does intermittent nutrition enterally normalise hormonal and metabolic responses to feeding in critically ill adults? A protocol for the DINE-Normal proof-of-concept randomised parallel-group study

Introduction Over half of patients who spend >48 hours in the intensive care unit (ICU) are fed via a nasogastric (NG) tube. Current guidance recommends continuous delivery of feed throughout the day and night. Emerging evidence from healthy human studies shows that NG feeding in an intermitt...

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Main Authors: Paul White, Matt Thomas, Javier T Gonzalez, Aravind V Ramesh, Anthony E Pickering, Danielle Milne, Borislava Borislavova, Clodagh Emer Beattie, Harry A Smith, Michael Ambler, Kati Hayes, James A Betts
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/11/e086540.full
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https://bmjopen.bmj.com/content/14/11/e086540.full

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