Prenatal pembrolizumab exposure as the potential link among recurrent necrotizing enterocolitis, neonatal diabetes mellitus and exocrine pancreatic insufficiency: a case report

Prenatal pembrolizumab exposure as the potential link among recurrent necrotizing enterocolitis, neonatal diabetes mellitus and exocrine pancreatic insufficiency: a case report

Abstract Background Necrotizing enterocolitis (NEC) is a serious complication predominantly affecting very low birth weight neonates, characterized by high mortality and long-term morbidity. Neonatal diabetes mellitus (NDM) is a rare condition with diverse etiologies, including genetic predispositio...

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Main Authors: Pasquale Castaldo, Luigi Altimari, Maria Grazia Capretti, Giulio Maltoni, Andrea Scozzarella, Vittoria Paoletti, Luigi Corvaglia, Arianna Aceti
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Italian Journal of Pediatrics
Subjects:
Necrotizing enterocolitis
Neonatal diabetes mellitus
Pembrolizumab
Case report
Maternal immune checkpoint inhibitor therapy
Online Access:https://doi.org/10.1186/s13052-025-02021-8
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https://doi.org/10.1186/s13052-025-02021-8

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