Oversecretion of CCL3 by Irradiation-Induced Senescent Osteocytes Mediates Bone Homeostasis Imbalance

Various stressors such as ionizing radiation (IR), chemotherapeutic agents, oxidative stress, and inflammatory responses can trigger the stress-induced premature senescence (SIPS) of cells in the bone microenvironment, including osteocytes. However, little is known about the mechanisms underlying th...

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Bibliographic Details
Main Authors: Fanyu Zhao, Haiqing Han, Jing Wang, Jianping Wang, Jianglong Zhai, Guoying Zhu
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/14/4/249
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