Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks
Purpose. To evaluate the efficacy and safety of the simultaneous use of short-term perfluoro-n-octane (PFO) with perfluoropropane (C3F8) gas to achieve retinal reattachment in eyes with rhegmatogenous retinal detachment (RRD) with proliferative vitreoretinopathy (PVR) grade C and multiple retinal br...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2020/6938627 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563299540008960 |
|---|---|
| author | Mohamed Farouk Abdelkader Shaaban Abd-Elhamid Mehany Elwan Ahmed Shawkat Abdelhalim |
| author_facet | Mohamed Farouk Abdelkader Shaaban Abd-Elhamid Mehany Elwan Ahmed Shawkat Abdelhalim |
| author_sort | Mohamed Farouk Abdelkader |
| collection | DOAJ |
| description | Purpose. To evaluate the efficacy and safety of the simultaneous use of short-term perfluoro-n-octane (PFO) with perfluoropropane (C3F8) gas to achieve retinal reattachment in eyes with rhegmatogenous retinal detachment (RRD) with proliferative vitreoretinopathy (PVR) grade C and multiple retinal breaks including inferior breaks. Design. This is a prospective interventional case series study. Patients and Methods. The study was a prospective noncomparative interventional study. It included 30 eyes of 30 patients who had RRD with PVR grade C and multiple retinal breaks including inferior tears attending the vitreoretinal unit of Minia University Hospital, Egypt. The mean age was 50.2 ± 10.63 years; 18 patients were females and 12 were males. Combined phacoemulsification and 23 G pars plana vitrectomy (PPV) with double retinal tamponade by C3F8 and PFO were done, and PFO was removed in 10–14 days. The patients were followed up for one year. The primary outcome was to achieve successful retinal reattachment, and the secondary outcomes were visual improvement and occurrence of complications. Results. Successful retinal reattachment was obtained in 28 eyes out of 30 (93.3%), and 2 eyes (6.7%) had recurrent RD. Best-corrected distance visual acuity (BCDVA) in logMAR was significantly improved from baseline 1.74 ± 0.05 to 0.93 ± 0.04, 0.82 ± 0.05, 0.80 ± 0.07, and 0.73 ± 0.055 at follow-up visits 3, 6, and 9 months and one year, respectively (P≤0.001). There were no serious ocular complications recorded. Conclusions. The results of this study indicated that primary vitrectomy with simultaneous use of both C3F8 and short-term PFO as retinal tamponades was effective and safe in the management of complex cases of RRD with PVR grade C and inferior breaks. This trial is registered with NCT04168255. |
| format | Article |
| id | doaj-art-7f744aa0e1b743bb8d2cfbb908f62e16 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-7f744aa0e1b743bb8d2cfbb908f62e162025-02-03T01:20:30ZengWileyJournal of Ophthalmology2090-004X2090-00582020-01-01202010.1155/2020/69386276938627Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior BreaksMohamed Farouk Abdelkader0Shaaban Abd-Elhamid Mehany Elwan1Ahmed Shawkat Abdelhalim2Ophthalmology Department, Faculty of Medicine, Minia University, El-Minia, EgyptOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, EgyptOphthalmology Department, Faculty of Medicine, Minia University, El-Minia, EgyptPurpose. To evaluate the efficacy and safety of the simultaneous use of short-term perfluoro-n-octane (PFO) with perfluoropropane (C3F8) gas to achieve retinal reattachment in eyes with rhegmatogenous retinal detachment (RRD) with proliferative vitreoretinopathy (PVR) grade C and multiple retinal breaks including inferior breaks. Design. This is a prospective interventional case series study. Patients and Methods. The study was a prospective noncomparative interventional study. It included 30 eyes of 30 patients who had RRD with PVR grade C and multiple retinal breaks including inferior tears attending the vitreoretinal unit of Minia University Hospital, Egypt. The mean age was 50.2 ± 10.63 years; 18 patients were females and 12 were males. Combined phacoemulsification and 23 G pars plana vitrectomy (PPV) with double retinal tamponade by C3F8 and PFO were done, and PFO was removed in 10–14 days. The patients were followed up for one year. The primary outcome was to achieve successful retinal reattachment, and the secondary outcomes were visual improvement and occurrence of complications. Results. Successful retinal reattachment was obtained in 28 eyes out of 30 (93.3%), and 2 eyes (6.7%) had recurrent RD. Best-corrected distance visual acuity (BCDVA) in logMAR was significantly improved from baseline 1.74 ± 0.05 to 0.93 ± 0.04, 0.82 ± 0.05, 0.80 ± 0.07, and 0.73 ± 0.055 at follow-up visits 3, 6, and 9 months and one year, respectively (P≤0.001). There were no serious ocular complications recorded. Conclusions. The results of this study indicated that primary vitrectomy with simultaneous use of both C3F8 and short-term PFO as retinal tamponades was effective and safe in the management of complex cases of RRD with PVR grade C and inferior breaks. This trial is registered with NCT04168255.http://dx.doi.org/10.1155/2020/6938627 |
| spellingShingle | Mohamed Farouk Abdelkader Shaaban Abd-Elhamid Mehany Elwan Ahmed Shawkat Abdelhalim Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks Journal of Ophthalmology |
| title | Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks |
| title_full | Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks |
| title_fullStr | Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks |
| title_full_unstemmed | Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks |
| title_short | Double Retinal Tamponade for Treatment of Rhegmatogenous Retinal Detachment with Proliferative Vitreoretinopathy and Inferior Breaks |
| title_sort | double retinal tamponade for treatment of rhegmatogenous retinal detachment with proliferative vitreoretinopathy and inferior breaks |
| url | http://dx.doi.org/10.1155/2020/6938627 |
| work_keys_str_mv | AT mohamedfaroukabdelkader doubleretinaltamponadefortreatmentofrhegmatogenousretinaldetachmentwithproliferativevitreoretinopathyandinferiorbreaks AT shaabanabdelhamidmehanyelwan doubleretinaltamponadefortreatmentofrhegmatogenousretinaldetachmentwithproliferativevitreoretinopathyandinferiorbreaks AT ahmedshawkatabdelhalim doubleretinaltamponadefortreatmentofrhegmatogenousretinaldetachmentwithproliferativevitreoretinopathyandinferiorbreaks |