RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study

RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study

Offspring of mothers with hypertensive disorders of pregnancy (HDP) are at increased risk of developing endothelial dysfunction and cardiovascular disease (CVD) in adulthood. MicroRNAs (miRNAs), as key regulators of endothelial cells, may contribute to the early onset of endothelial dysfunction. How...

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Main Authors: Nurul Iffah Mohd Isa, Aslah Nabilah Abdull Sukor, Saiful Effendi Syafruddin, Mohd Faizal Ahmad, Shahidee Zainal Abidin, Mohd Helmy Mokhtar, Azizah Ugusman, Adila A. Hamid
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
endothelial dysfunction
cardiovascular disease
human umbilical vein endothelial cells
hypertensive disorders of pregnancy
microRNA
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1520101/full
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