Tetrahydrobiopterin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Friend or Foe?

Tetrahydrobiopterin in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Friend or Foe?

Myalgic Encephalomyelitis or Chronic Fatigue Syndrome (ME/CFS) is a chronic multisystem disease characterized by severe muscle fatigue, pain, dizziness, and brain fog. The two most common symptoms are post-exertional malaise (PEM) and orthostatic intolerance (OI). ME/CFS patients with OI (ME+OI) suf...

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Bibliographic Details
Main Authors: A. F. M. Towheedur Rahman, Anna Benko, Sarojini Bulbule, Carl Gunnar Gottschalk, Leggy A. Arnold, Avik Roy
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biomolecules
Subjects:
tetrahydrobiopterin (BH4)
dihydrobiopterin (BH2)
pentose phosphate pathway (PPP)
ME/CFS
orthostatic intolerance (OI)
oxidative stress
Online Access:https://www.mdpi.com/2218-273X/15/1/102
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