Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits

This paper reports on the eco‐friendly synthesis of gold nanoparticles (AuNPs) using Solanum indicum fruit extract (SFE). We have evaluated various parameters for synthesis of AuNPs such as SFE (0.03%), HAuCl4 (0.5 mM) and reaction time (20 seconds). The synthesized AuNPs were characterized with dif...

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Main Authors: Punuri Jayasekhar Babu, Pragya Sharma, Sibyala Saranya, Ranjan Tamuli, Utpal Bora
Format: Article
Language:English
Published: Wiley 2013-04-01
Series:Nanomaterials and Nanotechnology
Subjects:
Online Access:http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/green-synthesis-and-characterization-of-biocompatible-gold-nanoparticles-using-solanum-indicum-fruit
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author Punuri Jayasekhar Babu
Pragya Sharma
Sibyala Saranya
Ranjan Tamuli
Utpal Bora
author_facet Punuri Jayasekhar Babu
Pragya Sharma
Sibyala Saranya
Ranjan Tamuli
Utpal Bora
author_sort Punuri Jayasekhar Babu
collection DOAJ
description This paper reports on the eco‐friendly synthesis of gold nanoparticles (AuNPs) using Solanum indicum fruit extract (SFE). We have evaluated various parameters for synthesis of AuNPs such as SFE (0.03%), HAuCl4 (0.5 mM) and reaction time (20 seconds). The synthesized AuNPs were characterized with different physical techniques such as transmission electron microscopy (TEM), Fourier transform infrared (FT‐IR) spectroscopy, X‐ray diffraction (XRD) and energy dispersive X‐ray spectroscopy (EDX). TEM experiments showed that AuNPs presented an anisotropic shape and size ranging from 5‐50nm. FT‐IR spectroscopy revealed that biomolecules containing an amine group (–NH2), a carbonyl group, –OH groups and other stabilizing functional groups were adsorbed on the surface of the synthesized AuNPs. EDX showed the presence of the elements on the surface of the AuNPs. The cytotoxicity of the synthesized AuNPs were tested on two different human cancer cell lines, HeLa and MCF‐7 and were found to be nontoxic, thus providing an opportunity to be used in biomedical applications.
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institution Kabale University
issn 1847-9804
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publishDate 2013-04-01
publisher Wiley
record_format Article
series Nanomaterials and Nanotechnology
spelling doaj-art-7ef96fc9f87f4d09b0aeca45f95ec1232025-02-03T06:47:12ZengWileyNanomaterials and Nanotechnology1847-98042013-04-0134http://dx.doi.org/10.5772/5660844465Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum FruitsPunuri Jayasekhar BabuPragya SharmaSibyala SaranyaRanjan TamuliUtpal BoraThis paper reports on the eco‐friendly synthesis of gold nanoparticles (AuNPs) using Solanum indicum fruit extract (SFE). We have evaluated various parameters for synthesis of AuNPs such as SFE (0.03%), HAuCl4 (0.5 mM) and reaction time (20 seconds). The synthesized AuNPs were characterized with different physical techniques such as transmission electron microscopy (TEM), Fourier transform infrared (FT‐IR) spectroscopy, X‐ray diffraction (XRD) and energy dispersive X‐ray spectroscopy (EDX). TEM experiments showed that AuNPs presented an anisotropic shape and size ranging from 5‐50nm. FT‐IR spectroscopy revealed that biomolecules containing an amine group (–NH2), a carbonyl group, –OH groups and other stabilizing functional groups were adsorbed on the surface of the synthesized AuNPs. EDX showed the presence of the elements on the surface of the AuNPs. The cytotoxicity of the synthesized AuNPs were tested on two different human cancer cell lines, HeLa and MCF‐7 and were found to be nontoxic, thus providing an opportunity to be used in biomedical applications.http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/green-synthesis-and-characterization-of-biocompatible-gold-nanoparticles-using-solanum-indicum-fruitSolanum indicumGold nanoparticlesCrystal growthselectron microscopyFourier transform infrared spectroscopynanostructureX‐ray diffraction
spellingShingle Punuri Jayasekhar Babu
Pragya Sharma
Sibyala Saranya
Ranjan Tamuli
Utpal Bora
Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
Nanomaterials and Nanotechnology
Solanum indicum
Gold nanoparticles
Crystal growths
electron microscopy
Fourier transform infrared spectroscopy
nanostructure
X‐ray diffraction
title Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
title_full Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
title_fullStr Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
title_full_unstemmed Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
title_short Green Synthesis and Characterization of Biocompatible Gold Nanoparticles Using Solanum indicum Fruits
title_sort green synthesis and characterization of biocompatible gold nanoparticles using solanum indicum fruits
topic Solanum indicum
Gold nanoparticles
Crystal growths
electron microscopy
Fourier transform infrared spectroscopy
nanostructure
X‐ray diffraction
url http://www.intechopen.com/journals/nanomaterials_and_nanotechnology/green-synthesis-and-characterization-of-biocompatible-gold-nanoparticles-using-solanum-indicum-fruit
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AT pragyasharma greensynthesisandcharacterizationofbiocompatiblegoldnanoparticlesusingsolanumindicumfruits
AT sibyalasaranya greensynthesisandcharacterizationofbiocompatiblegoldnanoparticlesusingsolanumindicumfruits
AT ranjantamuli greensynthesisandcharacterizationofbiocompatiblegoldnanoparticlesusingsolanumindicumfruits
AT utpalbora greensynthesisandcharacterizationofbiocompatiblegoldnanoparticlesusingsolanumindicumfruits