Urine methamphetamine-to-amphetamine ratio by LC-MS/MS to differentiate methamphetamine use from pharmaceutical impurity in patients prescribed amphetamine

Introduction: Patients compliant with prescribed amphetamine (AMPH) should not have detectable methamphetamine (METH) in their urine; detectable METH typically indicates illicit use. However, we have identified patients with results suggestive of METH as an impurity in prescribed AMPH. Objectives: D...

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Bibliographic Details
Main Authors: Lindsey Contella, Phillip Kang, Clara E. Wolf, Victoria L. Thomas, Melissa Gildenberg, Marion L. Snyder, Stacy E.F. Melanson, Nicole V. Tolan
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Mass Spectrometry and Advances in the Clinical Lab
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667145X25000203
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