Shattering the Amyloid Illusion: The Microbial Enigma of Alzheimer’s Disease Pathogenesis—From Gut Microbiota and Viruses to Brain Biofilms

For decades, Alzheimer’s Disease (AD) research has focused on the amyloid cascade hypothesis, which identifies amyloid-beta (Aβ) as the primary driver of the disease. However, the consistent failure of Aβ-targeted therapies to demonstrate efficacy, coupled with significant safety concerns, underscor...

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Bibliographic Details
Main Authors: Anna Onisiforou, Eleftheria G. Charalambous, Panos Zanos
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/1/90
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