A walk through the development of human leukocyte antigen typing: from serologic techniques to next-generation sequencing

Human leukocyte antigen (HLA) is a group of glycoproteins encoded by the major histocompatibility complex (MHC) that plays a pivotal role in the host's immune defense. Given that the MHC represents the most polymorphic region in the human genome, HLA typing is crucial in organ transplantation....

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Bibliographic Details
Main Authors: Haeyoun Choi, Eun-Jeong Choi, Hyoung-Jae Kim, In-Cheol Baek, Aegyeong Won, Su Jin Park, Tai-Gyu Kim, Yeun-Jun Chung
Format: Article
Language:English
Published: The Korean Society for Transplantation 2024-12-01
Series:Clinical Transplantation and Research
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Online Access:https://www.ctrjournal.org/journal/view.html?doi=10.4285/ctr.24.0055
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