Classification of psychedelics and psychoactive drugs based on brain-wide imaging of cellular c-Fos expression

Abstract Psilocybin, ketamine, and MDMA are psychoactive compounds that exert behavioral effects with distinguishable but also overlapping features. The growing interest in using these compounds as therapeutics necessitates preclinical assays that can accurately screen psychedelics and related analo...

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Bibliographic Details
Main Authors: Farid Aboharb, Pasha A. Davoudian, Ling-Xiao Shao, Clara Liao, Gillian N. Rzepka, Cassandra Wojtasiewicz, Jonathan Indajang, Mark Dibbs, Jocelyne Rondeau, Alexander M. Sherwood, Alfred P. Kaye, Alex C. Kwan
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56850-6
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