A simplified and efficient method for isolating small extracellular vesicles for comparative and comprehensive translational research

A simplified and efficient method for isolating small extracellular vesicles for comparative and comprehensive translational research

Abstract Small extracellular vesicles (sEVs) can provide information about the pathophysiology of the cells; therefore, sEVs have attracted considerable interest as possible diagnostic biomarkers. A key challenge lies in the necessity for simple and cost-effective sEV isolation methods to achieve hi...

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Main Authors: Prahalad Singh Bharti, Komal Rani, Rishabh Singh, Sanskriti Rai, Simran Rastogi, Manya Batra, Abhay Mishra, Sadaqa Zehra, Priya Kumari Gorai, Manda Venkata Sasidhar, Gyan Prakash Modi, Garima Malik, Neerja Rani, Kapil Dev, Thota Jagadeshwar Reddy, Krishna Kishore Inampudi, Fredrik Nikolajeff, Saroj Kumar
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Small extracellular vesicles
sEVs isolation
Nanoparticle tracking analysis
Human saliva
Human plasma
Cell culture media.
Online Access:https://doi.org/10.1038/s41598-025-99822-y
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https://doi.org/10.1038/s41598-025-99822-y

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